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Napa 125mg Beximco Pharma

HomeShopper Napa 125mg Beximco Pharma

By HomeShopper
Sold by HomeShopper
In Stock: 100
Children (6-12 years): ½ to 1 tablet 3 to 4 times daily. For long term treatment, it is wise not to exceed the dose beyond 2.6 gm/day.
-21%

Availability: In stock

Rs. 1,950

Rs. 1,550

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Paracetamol exhibits analgesic action by peripheral blockage of pain impulse generation. It produces antipyresis by inhibiting the hypothalamic heat-regulating center. Its weak anti-inflammatory activity is related to inhibition of prostaglandin synthesis in the CNS.

Paracetamol (Acetaminophen) is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis. Unlike NSAIDs, acetaminophen does not inhibit cyclooxygenase in peripheral tissues and, thus, has no peripheral anti-inflammatory effects. While aspirin acts as an irreversible inhibitor of COX and directly blocks the enzyme's active site, studies have found that acetaminophen indirectly blocks COX and that this blockade is ineffective in the presence of peroxides. This might explain why acetaminophen is effective in the central nervous system and in endothelial cells but not in platelets and immune cells which have high levels of peroxides. Studies also report data suggesting that acetaminophen selectively blocks a variant of the COX enzyme that is different from the known variants COX-1 and COX-2. This enzyme is now referred to as COX-3. Its exact mechanism of action is still poorly understood, but future research may provide further insight into how it works. The antipyretic properties of acetaminophen are likely due to direct effects on the heat-regulating centers of the hypothalamus resulting in peripheral vasodilation, sweating and hence heat dissipation.
General Brand HomeShopper
SKU HASHOM5D9B0C85EB168
Vendor HomeShopper
Features Weight 0.5000